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Pertussis in the Preantibiotic and Prevaccine Era, with Emphasis on Adult Pertussis
James D. Cherry
Clinical Infectious Diseases
Vol. 28, Supplement 2. Pertussis in Adults: Epidemiology, Signs, Symptoms, and Implications for Vaccination (Jun., 1999), pp. S107-S111
Published by: Oxford University Press
Stable URL: http://www.jstor.org/stable/4481904
Page Count: 5
You can always find the topics here!Topics: Whooping cough, Diseases, Cough, Epidemiology, Children, Vaccination, Child development, Infectious diseases, Epidemics, Mortality
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Pertussis was first recognized as an epidemic disease in the 16th century. The classic illness is a three-stage illness (catarrhal, spasmodic, and convalescent), with a distinctive cough, and its characteristics today are similar to those in the prevaccine era. In the prevaccine era, the calculated attack rate was 872/100,000 population, and the majority of cases occurred in children <5 years of age. On average, there were 7,300 deaths/year; the death rate began to decline before antimicrobial therapy and vaccination. Reported pertussis in adults was rare, but numerous investigators noted that atypical cases of pertussis were common in adults.
Clinical Infectious Diseases © 1999 Oxford University Press