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Conventional H5N9 Vaccine Suppresses Shedding in Specific-Pathogen-Free Birds Challenged with HPAI H5N1 A/Chicken/Yamaguchi/7/2004 (Una vacuna convencional H5N9 suprime la diseminación viral en ayes libres de patógenos específicos desafiadas con el virus de influenza aviar de alta patogenicidad A/ck/Yamaguchi/7/2004)

C. Terregino, A. Toffan, M. S. Beato, R. De Nardi, A. Drago and I. Capua
Avian Diseases
Vol. 51, No. 1, Supplement: Sixth International Symposium on Avian Influenza (Mar., 2007), pp. 495-497
Stable URL: http://www.jstor.org/stable/4493260
Page Count: 3
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Conventional H5N9 Vaccine Suppresses Shedding in Specific-Pathogen-Free Birds Challenged with HPAI H5N1 A/Chicken/Yamaguchi/7/2004 (Una vacuna convencional H5N9 suprime la diseminación viral en ayes libres de patógenos específicos desafiadas con el virus de influenza aviar de alta patogenicidad A/ck/Yamaguchi/7/2004)
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Abstract

Avian influenza represents one of the greatest concerns for public health that has emerged in recent times. Highly pathogenic avian influenza viruses belonging to the H5N1 subtype are endemic in Asia and are spreading in Europe and Africa. Vaccination is now considered a tool to support eradication efforts, provided it is appropriately managed. This study was carried out to establish the degree of clinical protection and reduction of viral shedding induced by a high-specification, commercially available avian influenza vaccine of a different lineage and containing a strain with a heterologous neuraminidase (H5N9 subtype) to the challenge virus isolate A/chicken/Yamaguchi/7/2004 (H5N1 subtype). /// La influenza aviar representa una de las mas grandes preocupaciones para la salud pública que haya emergido en los últimos tiempos. Los virus de influenza aviar de alta patogenicidad pertenecientes al subtipo H5N1 son endémicos en Asia y están diseminándose por Europa y África. La vacunación se reconoce como una herramienta para apoyar los esfuerzos de erradicación, siempre que esta se maneje adecuadamente. Este estudio se llevó a cabo con la finalidad de establecer el grado de protección clínica y el nivel de reducción en diseminación viral inducido por una vacuna disponible comercialmente que es altamente específica, de un linaje diferente y que contiene una cepa con una neuraminidasa heteróloga (subtipo H5N9) al virus utilizado para el desafío, en este caso el aislamiento A/ck/Yamaguchi/7/2004 (subtipo H5N1).

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