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Defective Production of Mitochondrial Ribosomes in the Poky Mutant of Neurospora crassa
M. R. Rifkin and D. J. L. Luck
Proceedings of the National Academy of Sciences of the United States of America
Vol. 68, No. 2 (Feb., 1971), pp. 287-290
Published by: National Academy of Sciences
Stable URL: http://www.jstor.org/stable/60361
Page Count: 4
You can always find the topics here!Topics: Ribosomes, Cytochromes, RNA, Monomers, Mitochondria, Steepest descent method, Gels, Neurospora crassa, Neurospora, Centrifugation
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A strain of Neurospora crassa containing a cytoplasmic mutation (poky) affecting mitochondrial function is shown to be deficient in small ribosomal subunits in the mitochondrion during the exponential growth phase. In the stationary growth phase, small subunits are more abundant and are present in mitochondrial ribosomal monomers. This change can be correlated with the return of mitochondrial cytochrome content to amounts approaching those of wild type mitochondria. The ribosomal defect shows an extrachromosomal pattern of inheritance in crosses of poky with wild type.
Proceedings of the National Academy of Sciences of the United States of America © 1971 National Academy of Sciences