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Serum Factor Requirements of Normal and Simian Virus 40-Transformed 3T3 Mouse Fibroblasts
Dieter Paul, Allan Lipton and Ingrid Klinger
Proceedings of the National Academy of Sciences of the United States of America
Vol. 68, No. 3 (Mar., 1971), pp. 645-648
Published by: National Academy of Sciences
Stable URL: http://www.jstor.org/stable/60533
Page Count: 4
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Evidence is presented to show the presence in normal rat serum of four different serum factors essential for growth of 3T3 or SV40-transformed 3T3 mouse fibroblasts: a factor that specifically promotes growth of normal 3T3 cells; two factors that specifically promote growth of transformed 3T3 cells; and a factor that sustains viability of both normal and transformed 3T3 cells in serum-free medium, probably without inducing growth of the cells. These factors are separated and partially purified.
Proceedings of the National Academy of Sciences of the United States of America © 1971 National Academy of Sciences