Access

You are not currently logged in.

Access your personal account or get JSTOR access through your library or other institution:

login

Log in to your personal account or through your institution.

If You Use a Screen Reader

This content is available through Read Online (Free) program, which relies on page scans. Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.

Control of the Rat Pineal Gland by Light Spectra

Daniel P. Cardinali, Frances Larin and Richard J. Wurtman
Proceedings of the National Academy of Sciences of the United States of America
Vol. 69, No. 8 (Aug., 1972), pp. 2003-2005
Stable URL: http://www.jstor.org/stable/61460
Page Count: 3
  • Read Online (Free)
  • Subscribe ($19.50)
  • Cite this Item
Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Control of the Rat Pineal Gland by Light Spectra
Preview not available

Abstract

Control of pineal hydroxyindole-O-methyl transferase (S-adenosylmethionine:N-acetylserotonin-O-methyl transferase; EC 2.1.1.4) by light spectra was determined by placing groups of rats previously housed in continuous darkness under one of seven light sources for 96 hr; rats were exposed to the same intensity of irradiation. Activity of the enzyme was lowest in rats maintained under green light (λ peak = 530 nm); blue and yellow light were somewhat less effective; red and ultraviolet light did not significantly lower the enzyme activity. The suppression of pineal hydroxyindole-O-methyl transferase by full-spectrum light sources could be correlated with the proportions of their spectral outputs in the blue-green-yellow range. These observations suggest that the retinal photopigment that mediates pineal responses to light in rats is rhodopsin or another compound with similar absorption properties.

Page Thumbnails

  • Thumbnail: Page 
2003
    2003
  • Thumbnail: Page 
2004
    2004
  • Thumbnail: Page 
2005
    2005