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Linking Numbers and Nucleosomes

F. H. C. Crick
Proceedings of the National Academy of Sciences of the United States of America
Vol. 73, No. 8 (Aug., 1976), pp. 2639-2643
Stable URL: http://www.jstor.org/stable/66019
Page Count: 5
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Linking Numbers and Nucleosomes
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Abstract

In considering supercoils formed by closed double-stranded molecules of DNA certain mathematical concepts, such as the linking number and the twist, are needed. The meaning of these for a closed ribbon is explained and also that of the writhing number of a closed curve. Some simple examples are given, some of which may be relevant to the structure of chromatin.

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