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Electrogenic Sodium Pump in Pancreatic Acinar Cells

O. H. Petersen
Proceedings of the Royal Society of London. Series B, Biological Sciences
Vol. 184, No. 1074 (Aug. 31, 1973), pp. 115-119
Published by: Royal Society
Stable URL: http://www.jstor.org/stable/76147
Page Count: 5
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Electrogenic Sodium Pump in Pancreatic Acinar Cells
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Abstract

Electrogenic sodium pumps have been described in many excitable tissues, but hitherto not with certainty in epithelial tissues. In the present work it is shown that readmission of potassium to the bathing solution of mouse pancreatic tissue previously deprived of potassium, causes a marked hyperpolarization of the acinar cell membrane. This hyperpolarization is abolished reversibly by strophanthin-G. This indicates the presence of electrogenic sodium pumping in pancreatic acinar cells.

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