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Succinic Dehydrogenase-Cytochrome System of Cells Intracellular Respiratory System Catalysing Aerobic Oxidation of Succinic Acid

D. Keilin and E. F. Hartree
Proceedings of the Royal Society of London. Series B, Biological Sciences
Vol. 129, No. 856 (Oct. 24, 1940), pp. 277-306
Published by: Royal Society
Stable URL: http://www.jstor.org/stable/82300
Page Count: 30
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Since scans are not currently available to screen readers, please contact JSTOR User Support for access. We'll provide a PDF copy for your screen reader.
Succinic Dehydrogenase-Cytochrome System of Cells Intracellular Respiratory System Catalysing Aerobic Oxidation of Succinic Acid
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Abstract

Succinic dehydrogenase-cytochrome system, even in the cell-free colloidal preparation, behaves like a true respiratory system of the cell, showing the high catalytic activity and being affected by all the inhibitors in the same way and to the same degree as the respiration of intact cells. The efficiency of this system depends not only on the integrity of all its components but also on that of the colloidal structure which supports them and assures their mutual accessibility. The paper deals with the properties of each of the components of the system and with the mechanism of their interreactions.

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