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The effectiveness of radon-daughter inhalation and irradiation with fission neutrons and γ rays in the induction of lung carcinomas in Sprague-Dawley rats at low doses is compared. Earlier reports which compared radon-daughter inhalations and neutron irradiations over a wider range of doses were based on dosimetry for the radon-daughter inhalations which has recently been found to be faulty. In the present analysis, low-dose experiments were designed to derive revised equivalence ratios between radon-daughter exposures, and fission neutron or γ irradiations. The equivalence is approximately 15 working level months (WLM) of radon daughters to 10 mGy of neutrons (the earlier value was 30 WLM to 10 mGy). The relative biological effectiveness (RBE) of neutrons is 50 or more at a γ-ray dose of 1 Gy. In these experiments with low doses and exposures, the lifetime incidences can be estimated from the raw incidences, while the derivation of the time dependence of the prevalence is essential for the estimation of RBE values and equivalence ratios.
Radiation Research publishes articles dealing with radiation effects and related subjects in the areas of physics, chemistry, biology and medicine, including epidemiology and translational research. The term radiation is used in its broadest sense and includes specifically ionizing and ultraviolet, visible and infrared light as well as microwaves, ultrasound and heat. Related subjects include (but are not limited to) studies with chemical agents contributing to the understanding of the effects of radiation, isotope techniques, and dosimetry methods and instrumentation.
The Radiation Research Society's objectives are threefold: To encourage in the broadest manner the advancement of radiation research in all areas of the natural sciences; To facilitate cooperative research between the disciplines of physics, chemistry, biology and medicine in the study of the properties and effects of radiation; To promote dissemination of knowledge in these and related fields through publications, meetings and educational symposia.
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